Veterinary Archives, Vol. 74 No. 2, 2004.
Original scientific paper
Comparative efficacy of various indigenous and allopathic drugs against fasciolosis in buffaloes.
Azhar Maqbool
; Department of Parasitology, University of Veterinary and Animal Sciences, Lahore, Pakistan
Chaudhry Sikandar Hayat
; Faculty of Veterinary Science, University of Agriculture Faisalabad
Akhtar Tanveer
; Department of Zoology, University of the Punjab, Lahore, Pakistan
Abstract
One hundred and eighty buffaloes were used in 18 controlled experiments to compare the efficacy of certain indigenous drugs, including Nigella sativa seeds, Fumaria parviflora aerial parts, Caesalpinia crista seeds, and Saussurea lappa roots with triclabendazole against fasciolosis. Efficacy was quantified by determining the difference of eggs per gram faeces (EPG) pre- and post-treatment. Nigella sativa seeds, after a single dose of 30, 40 and 50 mg/kg body mass, reduced EPG by 54.16, 57.4 and 58.33 per cent, respectively. After the second dose the respective reduction in EPG was 79.16, 80.85 and 81.25 per cent. Fumaria parviflora aerial parts at a rate of 40, 50 and 60 mg/kg body mass were 50.0, 57.44 and 78.72 per cent, respectively, whereas efficacy at two dose levels with the same dose rate was 82.6, 89.36 and 95.74 per cent, respectively. Caesalpinia crista seeds at 30, 40 and 50 mg/kg body mass were 48.9, 50.0 and 57.7 per cent effective, respectively, whereas efficacy at two dose levels was 80.0, 84.09 and 86.6 per cent, respectively. Saussurea lappa at a rate of 50, 100 and 200 mg/kg body mass was 46.6, 57.4 and 61.7 per cent effective, respectively, at one dose level and was 62.2, 72.3 and 78.7 per cent effective at two dose levels. Triclabendazole at one dose level at a rate of 10 mg/kg body mass was 82.6 per cent effective and at two dose levels it was 95.7 per cent effective. The efficacy order was triclabendazole, Fumaria parviflora, Caesalpinia crista, Nigella sativa, and Saussurea lappa. No side effects were noted due to the use of any of these plant-origin drugs.
Keywords
indigenous and allopathic drugs; fasciolosis; buffaloes
Hrčak ID:
67837
URI
Publication date:
22.4.2004.
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