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Gynaecologia et perinatologia : journal for gynaecology, perinatology, reproductive medicine and ultrasonic diagnostics, Vol. 19 No. 2, 2010.

Original scientific paper

DIAGNOSIS OF HYPERGLYCEMIA IN PREGNANCY

Josip Đelmiš orcid id orcid.org/0000-0002-7332-5936 ; Medicinski fakulteta Sveučilišta u Zagrebu, Klinika za ženske bolesti i porode KBC-a Zagreb, Petrova 13, Zagreb, Hrvatska
Marina Ivanišević orcid id orcid.org/0000-0001-6478-1174 ; Medicinski fakulteta Sveučilišta u Zagrebu, Klinika za ženske bolesti i porode KBC-a Zagreb, Petrova 13, Zagreb, Hrvatska
Josip Juras orcid id orcid.org/0000-0002-1801-5732 ; Medicinski fakulteta Sveučilišta u Zagrebu, Klinika za ženske bolesti i porode KBC-a Zagreb, Petrova 13, Zagreb, Hrvatska
Mislav Herman ; Medicinski fakulteta Sveučilišta u Zagrebu, Klinika za ženske bolesti i porode KBC-a Zagreb, Petrova 13, Zagreb, Hrvatska

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Abstract

HAPO study (Hyperglycemia Adverse Pregnancy Outcome) was designed to establish the more accurate levels in gestational diabetics where more active intervention will be necessary.11 The goal of HAPO study was to clarify the association between various glucose intolerance stages and adverse perinatal outcomes in the people without pregestational diabetes. It was important also for the HAPO study to propose new criteria for diagnosis of gestational diabetes (GDM). The proposition of the HAPO study for diagnose of GDM is defined by measuring the glucose concentration in venous plasma of the mother, when the results of the measuring are equal or above the thresholds: a) any fasting value equal or more than 5.1 mmol/L; b) after 75 grams glucosae load (oGTT) 1 hour measurement equal or more than 10 mmol/L and/or 2 hours measurement equal or more than 8.5 mmol/L. Overt diabetes during pregnancy is diagnosed when fasting glucose equals or more than 7 mmol/L and when 2 hour glucose concentration after 75 grams load (oGTT) equals or more 11.1 mmol/L. Any random plasma glucose of 11.1 mmol/L or more is the initial measure, the tentative diagnosis of overt diabetes in pregnancy should be confirmed by FPG or by HbA1c.

Keywords

hyperglycemia; diabetes; gestational diabetes; glucose tolerance test; HAPO study

Hrčak ID:

68422

URI

https://hrcak.srce.hr/68422

Publication date:

1.6.2010.

Article data in other languages: croatian

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