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Periodicum biologorum, Vol. 113 No. 2, 2011.

Review article

Local anaesthetic toxicity

Višnja Nesek Adam orcid id orcid.org/0000-0002-6521-4136 ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Sveti Duh Sveti Duh 64, Zagreb, Croatia
ANA MARKIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Sveti Duh Sveti, Duh 64, Zagreb, Croatia
KATARINA ŠAKIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Sveti Duh, Sveti Duh 64, Zagreb, Croatia
ELVIRA GRIZELJ STOJČIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Sveti Duh, Sveti Duh 64, Zagreb, Croatia
VIVIANA MRŠIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Sveti Duh, Sveti Duh 64, Zagreb, Croatia
DINKO TONKOVIĆ ; Department of Anaesthesiology, Reanimatology and Intensive Care, Clinical hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia

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Abstract

Local anaesthetic drugs arewidely used for the provision of regional anaesthesia and analgesia. When used properly, they are safe and effective and have only few side effects. However, in case of an accidental intravascular injection or an injection of excessive dose, they can be toxic and neurologic and cardiovascular symptoms may occur. Systemic toxicity, although a rare complication, can be life threatening and resistant to treatment. This review offers a brief overview of the current understanding of the circumstances
that cause systemic and cardiovascular toxicity in the daily clinical
practice and the management of clinical signs and symptoms.

Keywords

Hrčak ID:

68897

URI

https://hrcak.srce.hr/68897

Publication date:

1.6.2011.

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