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Periodicum biologorum, Vol. 113 No. 2, 2011.

Original scientific paper

Unilateral bupivacaine-fentanyl or bupivacaine-sufentanil spinal anaesthesia for arthroscopic knee surgery

RENATA KROBOT ; General hospital Varaždin, Department of anaesthesiology and intensive care, Ivana Meštrovića 2, 42000 Varaždin, Croatia
JADRANKA PREMUŽIĆ ; General hospital Varaždin, Department of anaesthesiology and intensive care, Ivana Meštrovića 2, 42000 Varaždin, Croatia
PATRICIA GRBČIĆ ; General hospital Varaždin, Department of anaesthesiology and intensive care, Ivana Meštrovića 2, 42000 Varaždin, Croatia
NENAD VUCELIĆ ; General hospital Varaždin, Department of anaesthesiology and intensive care, Ivana Meštrovića 2, 42000 Varaždin, Croatia

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Abstract

Background and purpose: Unilateral spinal anaesthesia provides high
cardiovascular stability and short ambulatory stay. Intrathecal coadministration od local anaesthetics and opioids has potent synergistic analgesic effect. We compared unilateral hyperbaric bupivacaine spinal anaesthesia with fentanyl or sufentanil in patients undergoing knee arthroscopy.

Materials and methods: 40 ASA I-II adults received unilateral spinal
anaesthesia with hyperbaric bupivacaine 4mg coadministered with either fentanyl 20μg (Group F,n=20) or sufentanil 2 μg (Group S, n=20). Sensory and motor block, hemodynamic data, side-effects and time to first analgesic were recorded.

Results: Anaesthesia was successful in all 40 patients. Upper level of sensory block on operative leg was Th12 (Th12-Th8) in Group F and Th12 (Th11-Th9) in Group S, P=0.89. Complete motor block had 5 (25%) Group F and 3 (15%) Group S patients, P=0.69. uration of motor block was 78 ± 15 and 77 ± 13 min in Group F and Group S, respectively, P=0.89. Maximum decrease of baseline systolic arterial pressure was 16 ± 9 in Group F and 17 ± 7% in Group S, P=0.81 and of HR 16 ± 7 and 16 ±8%, P=0.90, respectively. Time to first analgesic was 285 ± 123 min in Group F and 355 ± 110 min in Group S, P=0.04. Pruritus had 7 (35%) Group F and 5 (25%) Group S patients, P=0.73.

Conclusions: Unilateral hyperbaric bupivacaine spinal anaesthesia with fentanyl or sufentanil resulted in similar sensory and motor block and cardiovascular stability but bupivacaine-sufentanil combination provided prolonged first analgesic time

Keywords

Hrčak ID:

69017

URI

https://hrcak.srce.hr/69017

Publication date:

1.6.2011.

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