Review article

Treatment of the pregnancy hypertensive disorders

Dubravko Habek orcid.org/0000-0003-1304-9279 ; Klinika za ginekologiju i porodništvo Medicinskog fakulteta Sveučilišta u Zagrebu i Kliničke bolnice "Sveti Duh", Zagreb
Sandra Moslavac ; Poliklinika "Sunce" Zagreb, Interni odjel
Jasna Čerkez-Habek ; Poliklinika "Sunce" Zagreb, Interni odjel

Abstract

The management of preeclampsia includes antihypertensive therapy, anticonvulsant prophylaxis, controlled volume expansion (oncotic therapy), treatment of coagulation disorders and termination of
pregnancy. Antihypertensives include nifedipin, urapidil, labetalol, methyldopa, dihydralazine and magnesiumsulfat.
Oncotic treatment with 6% hydroxyethyl starch or dextrans is used to improve the reduced microperfusion of the uteroplacental unit, isovolemic hemodilution, and thromboprophylaxis. Aspirin therapy
failed to show any perinatal outcome improvement. Low molecular heparin is recommended as prophylaxis in severe preeclampsia, severe chronic hypertension, nephropathy, kidney transplantation, and antiphospholipid antibodies. The treatment requires monitoring of the maternal hemodynamic and coagulation status, and of the fetoplacental unit status by biophysical profile and doppler sonography control.

Keywords

hypertension; pregnancy; therapy

Hrčak ID:

70295

URI

https://hrcak.srce.hr/70295

Publication date:

6.7.2011.

Article data in other languages: croatian

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