Case report

DIGOXIN AND AMIODARON IN FETAL SUSTAINED SUPRAVENTRICULAR TACHYCARDIA AND NONIMMUNE HYDROPS

Vesna Sokol ; Department of Obstet. & Gynecol. Univ. Medical School of Zagreb, Petrova 13, Zagreb
Josip Juras ; Clinical Hospital Centre Zagreb, Department of Obstetrics and Gynecology,Univ. Medical School of Zagreb, Petrova 13, Zagreb
Ivan Malčić ; Department of pediatrics, University Clinical Centre Zagreb
Jozo Blajić ; Clinical Hospital Centre Zagreb, Department of Obstetrics and Gynecology,Univ. Medical School of Zagreb, Petrova 13, Zagreb
Marina Ivanišević ; Clinical Hospital Centre Zagreb, Department of Obstetrics and Gynecology,Univ. Medical School of Zagreb, Petrova 13, Zagreb

Abstract

Supraventricular tachycardia is the most common and clinically significant form of sustained fetal tachyarrhythmia in pregnancy; depending on duration and high rate variability heart failure and nonimmune hydrops may develop which are associated with a high incidence of perinatal mortality. Doppler/echo diagnosis is usually accidental during second and third trimester of pregnancy. Therapeutic goals are cardioconversion to sinus rhythm and recovery of heart failure. We present a case of fetal supraventricualr tachycardia diagnosed at 29 weeks of gestation with nonimmune hydrops. Treatment with digoxin and amiodarone was successful. The heart rate restored to sinus rhythm and nonimmune hydrops resolved within three weeks of treatment. Therapy with two drugs that act synergistically may be more efficient than monotherapy in blocking likely atrio-ventricular reentry mechanism by accessory pathway in sustained supraventricular tachycardia, thus allowing resolution of hydrops with favorable management outcome.

Keywords

fetalus; tachycardia supraventricular; fetal hydrops; digoxin; amiodarone

Hrčak ID:

70300

URI

https://hrcak.srce.hr/70300

Publication date:

1.3.2011.

Article data in other languages: croatian

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