Cardiologia Croatica, Vol. 6 No. 3-4, 2011.
Review article
Potential cardiovascular effects of anxiolytics.
Viktor Čulić
orcid.org/0000-0002-4026-0195
; University Hospital Centre Split, Split, Croatia
Olga Šegvić
; University Hospital Centre Split, Split, Croatia
Abstract
Besides traditional risk factors of the occurrence of cardiovascular diseases, various psychological and
social factors attract ever greater attention, whereby anxiety is
the factor that is more and more mentioned among them. Anxiety disorders increase a risk of occurrence of ventricular arrhythmia and occurrence of sudden cardiac death as a consequence of damaged balance of autonomic nervous system and
reduced baroflex control. Anxious persons also show a higher
risk of occurrence of coronary heart disease and myocardial
infarction. The drugs from the group of anxiolytics could have
positive cardiovascular effects that would be mediated by decreased anxiety and total sympathetic activity, prevented arrhythmogenesis, reduced peripheral vascular resistance, lowered blood pressure, aortic pressure and pressure in pulmonary artery and the pressure in the left heart at the end of the
diastole and a series of other mechanisms.
Keywords
anxiolytics; anxiety; sudden cardiac death; cardiovascular diseases
Hrčak ID:
71482
URI
Publication date:
30.3.2011.
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