Review article

What is new in the first European Society of Cardiology and European Atherosclerosis Society Guidelines for the management of dyslipidaemias?

Željko Reiner ; University Hospital Centre Zagreb, Zagreb, Croatia

Abstract

The first European guidelines for the management
of dyslipidaemias produced jointly by the European
Society of Cardiology and the European Atherosclerosis Society
deal with the management of dyslipidaemias as an integral
and important part of cardiovascular diseases (CVD)
prevention. According to them, in patients at very high CVD
risk (established CVD, type 2 diabetes, type 1 diabetes with
target organ damage, moderate to severe chronic kidney disease
or a SCORE level ≥10 %) the LDL-cholesterol goal
should be <1.8 mmol/L and/or reduced by a least 50% when
target level cannot be reached. In patients at high CVD risk
(markedly elevated single risk factors eg. hypercholesterolaemia,
and SCORE level ≥5 to <10%) a LDL-cholesterol
goal <2.5 mmol/L should be considered. In subjects at moderate
risk (SCORE level >1 to ≤5%) LDL-cholesterol goal
<3.0 mmol/L should be considered and in those at low risk
(SCORE level <1%) either no lipid intervention or, if LDLcholesterol
is <2.5mmol/L, only a lifestyle intervention is advised.
The guidelines also address for the first time some other
important issues such as treatment of high triglycerides
and low HDL-cholesterol, familial dyslipidaemias, dietary
supplements and functional foods active on plasma lipid values,
lipid-lowering drug combinations, management of dyslipidaemias
in children, women and the elderly, management
of dyslipidaemias in different clinical settings such as
diabetes and metabolic syndrome, patients with acute coronary
syndrome and those undergoing percutaneous coronary
interventions, patients with renal disease, peripheral artery
disease, stroke, aortic aneurysm, human immunodeficiency
patients etc.

Keywords

dyslipidaemias; cholesterol; triglycerides; HDL-cholesterol; LDL-cholesterol; cardiovascular diseases

Hrčak ID:

71836

URI

https://hrcak.srce.hr/71836

Publication date:

20.9.2011.

Article data in other languages: croatian

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