Original scientific paper

Acute L-alanyl-L-glutamine ingestion during short duration, high intensity exercise and a mild hydration stress

Jay R. Hoffman orcid.org/0000-0002-5696-4605 ; University of Central Florida, Sport and Exercise Science, Orlando, Florida, USA
Nicholas A. Ratamess ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Jie Kang ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Stephanie L. Rashti ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Neil Kelly ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Adam M. Gonzalez ; University of Central Florida, Sport and Exercise Science, Orlando, Florida, USA
Michael Stec ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Steven Anderson ; The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA
Brooke L. Bailey ; University of Connecticut, Department of Kinesiology, Storrs, Connecticut, USA
Linda M. Yamamoto ; University of Connecticut, Department of Kinesiology, Storrs, Connecticut, USA
Lindsay L. Hom ; University of Connecticut, Department of Kinesiology, Storrs, Connecticut, USA
Brian R. Kupchak ; University of Connecticut, Department of Kinesiology, Storrs, Connecticut, USA
Carl M. Maresh ; University of Connecticut, Department of Kinesiology, Storrs, Connecticut, USA

Abstract

The effect of acute L-alanyl-L-glutamine (AG) ingestion on selected hormonal and electrolyte measures was examined during repetitive, short duration, high intensity exercise with mild hypohydration. Subjects (20.3±1.1 yrs; 180.3±10.4 cm; 83.1±14.0 kg; 11.6±3.6% body fat) reported to the Human Performance Laboratory on four occasions. During each trial subjects were hypohydrated to -2.5% of their baseline body mass. During one trial (DHY) subjects rested in a recumbent position for 45 minutes before commencing the exercise session. During the other three trials subjects were rehydrated to 1.5% of their baseline body mass, before exercise, by drinking water only (W), or with two different doses of AG – a low dose (LDAG:
0.05 g�kg-1) and a high dose (HDAG: 0.2 g�kg-1). The exercise protocol consisted of ten 10-second sprints on a cycle ergometer with a 1-min rest between each sprint. Blood draws were collected once the subject achieved the desired level of hypohydration, immediately pre-exercise, immediately post-exercise, and 24 hrs postexercise.
Blood samples were analyzed for glutamine, potassium, sodium, aldosterone, arginine vasopressin, C-reactive protein, interleukin-6, malondialdehyde, testosterone, cortisol, ACTH, and growth hormone. The area under the curve (AUC) analysis demonstrated significantly greater sodium concentrations for DHY compared to all other trials. The AUC analysis for aldosterone showed significantly lower concentrations at LDAG compared to DHY. No other differences between trials were observed in any other hormonal or biochemical responses. AG ingestion during a short duration, anaerobic exercise and mild hypohydration stress had a limited effect on selected hormonal and biochemical measures.

Keywords

endocrine response; immune response; fluid regulatory hormones; electrolytes; anabolic hormones

Hrčak ID:

75432

URI

https://hrcak.srce.hr/75432

Publication date:

30.12.2011.

Article data in other languages: croatian

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