Acta clinica Croatica, Vol. 50 No. 2, 2011.
Original scientific paper
Metabolic Syndrome and Outcome in Patients with Acute Myocardial Infarction
Zdravko Babić
orcid.org/0000-0002-7060-8375
Marin Pavlov
Nikola Bulj
Vjeran Nikolić Heitzler
Veselin Mitrović
Christian Hamm
Michael Weber
Abstract
The impact of the metabolic syndrome/insulin resistance syndrome (MS/IR S) on the severity and prognosis of acute ST elevation myocardial infarction (STEMI ) treated with primary percutaneous coronary intervention (PCI) was assessed using the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) definition from 2003. A total of 385 patients having suffered acute STEMI and treated with primary PCI over a two-year period were divided into two groups (with and without MS/IR S) and compared according to the parameters of severity (clinical, laboratory, echocardiography, coronary angiography parameters and complications) and prognosis using major adverse cardiovascular events (MACE) during the six-month follow-up of acute STEMI . In comparison with control group, the MS/IR S group of patients had worse or similar results of almost all study parameters of severity (hospital days 6.5 vs. 6.5, cardiogenic shock 2.9% vs. 2.6%, cardiac arrest 6.8% vs. 5.2%, reinfarction 0.5 vs. 1.6%) and prognosis (total MACE 30.7 vs. 30.7%), however, none of the differences reached statistical significance. It is concluded that the unexpected lack of such differences in MS/IR S could be due to the absence of waist-to-hip ratio in the definition and other open questions in metabolic syndrome in general.
Keywords
Metabolic syndrome X; Myocardial infarction
Hrčak ID:
79307
URI
Publication date:
28.6.2011.
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