Skip to the main content

Chemical and Biochemical Engineering Quarterly, Vol. 26 No. 1, 2012.

Original scientific paper

Lipase-catalyzed Continuous Ring-opening Polymerization of ε-Caprolactone in a Packed-bed Reactor

M. J. Zhang ; State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, People’s Republic of China
E. Z. Su ; State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, People’s Republic of China
J. P. Lin ; State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, People’s Republic of China
D. Z. Wei ; State Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, People’s Republic of China

Full text: english pdf 188 Kb

page 1-6

downloads: 526

cite

Abstract

A packed-bed reactor (PBR) system was developed for continuous lipase-catalyzed ring-opening polymerization of -caprolactone (ε-CL). The parameters affecting the poly(ε-caprolactone) (PCL) production in the PBR such as residence time, height to diameter (H/D) ratio, and monomer feed concentration were investigated. Monomer conversion of ε-CL increased with the increase of residence time, reached the highest (over 98 %) at the residence time of 12 min. And under this residence time it would almost not change even if the H/D ratio varied from 4 to 20 or the monomer concentration varied from 0.2 to 2.25 mol L–1. The number-average molecular mass (Mn) of PCL did not change in agreement with the monomer conversion, and approached the maximal values of 15600 g mol–1 with polydispersity index (PDI) of 2.1 under 20 min residence time, 12.0 H/D ratio and 1.75 mol L–1 monomer concentration. The Mn of PCL maintained around 15600 g mol–1 without appreciable loss during the long-term operation of 460 h with the PCL productivity of 19.15 g g–1 enzyme d–1).

Keywords

Packed-bed reactor (PBR); lipase; ring-opening polymerization; poly(ε-caprolactone)

Hrčak ID:

79329

URI

https://hrcak.srce.hr/79329

Publication date:

1.4.2012.

Visits: 1.295 *