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Review article

Restless Legs Syndrome (RLS)

Valentina Matijević Mikelić orcid id orcid.org/0000-0003-0096-2034 ; University Department of Rheumatology, Physical Medicine and Rehabilitation, Clinical Hospital Centre
Sandra Morović ; Clinical Hospital Centre


Full text: croatian doc 71 Kb

page 93-100

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Abstract

Restless legs syndrome (abr. RLS) or Wittmaack-Ekbom syndrome is characterized by an irresistible urge to move body in order to stop uncomfortable or odd sensations. It most commonly affects the legs, but can affect the arms, torso, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief. Patophysiology of RLS is still unclear, but studies point towards functional dopamine disfunction. Depending on etiology, RLS can be primary or secondary. Both are usually worsend after any kind of surgery. Treatment of RLS comprise of identifying the cause of symptoms when possible. Pharmacotherapy of primary RLS includes dopamine agonists as the first line drugs for everyday symptoms, anticonvulsants and opioids for treatment of resistant cases, as well as levodopa and benzodizepines. In treating secondary RLS iron supplements are used. It is important to avoid the drugs that can worsen RLS or cause simptoms of RLS, as well as treating diseases that may be the cause of RLS.

Keywords

restless legs syndrome; psychomotor agitation; treatment; diagnosis; dopamine

Hrčak ID:

79527

URI

https://hrcak.srce.hr/79527

Publication date:

1.3.2012.

Article data in other languages: croatian

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