Case report

Molecular epidemiology of Mycobacterium tuberculosis transmission between cattle and man - a case report.

Silvio Špičić orcid.org/0000-0001-8317-5831 ; Croatian Veterinary Institute, Zagreb, Croatia
Mateja Pate ; University of Ljubljana, Veterinary Faculty, Ljubljana, Slovenia
Sanja Duvnjak ; Croatian Veterinary Institute, Zagreb, Croatia
Vera Katalinić-Janković ; Croatian National Institute of Public Health, Zagreb, Croatia
Mihaela Obrovac ; Croatian National Institute of Public Health, Zagreb, Croatia
Danko Dežđek ; Croatian Veterinary Institute, Zagreb, Croatia
Gordan Kompes ; Croatian Veterinary Institute, Zagreb, Croatia
Boris Habrun ; Croatian Veterinary Institute, Zagreb, Croatia
Matjaž Ocepek ; University of Ljubljana, Veterinary Faculty, Ljubljana, Slovenia
Željko Cvetnić ; Croatian Veterinary Institute, Zagreb, Croatia

Abstract

We describe a case of transmission of Mycobacterium (M.) tuberculosis infection from a man to cattle. M. tuberculosis was isolated from the bronchial lymph nodes of a heifer that reacted positively to bovine tuberculin but showed no gross pathological changes at slaughter. The cattle owner died of tuberculosis the same year the heifer was diagnosed with M. tuberculosis infection. M. tuberculosis strains isolated from the heifer and its owner were genotyped by mycobacterial interspersed repetitive units - variable number tandem repeat (MIRUVNTR) typing, which revealed identical MIRU profiles for both isolates. This is the first described case of M. tuberculosis infection in cattle and the first case of human-to-animal transmission of M. tuberculosis in Croatia.

Keywords

Mycobactrium tuberculosis; cattle; Croatia

Hrčak ID:

80699

URI

https://hrcak.srce.hr/80699

Publication date:

27.4.2012.

Article data in other languages: croatian

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