Review article
https://doi.org/10.2478/10004-1254-63-2012-2199
Ototoxic Substances at the Workplace: A Brief Update
Eberhardt Nies
; Institute for Occupational Safety and Health (IFA) of the German Social Accident Insurance, Sankt Augustin, Germany
Abstract
Ototoxic chemicals can impair the sense of hearing and balance. Lately, efforts have been intensifi ed to compile evidence-based lists of workplace agents with ototoxic properties. This article gives a rough overview of the latest relevant publications, which confirm that toluene, styrene, and lead should receive particular attention as ototoxic substances at the workplace. Moreover, there is sufficient evidence that occupational exposure to trichloroethylene, mercury, carbon monoxide, and carbon disulfide can affect the ear. Based on the existing information, industrial hygienists should make sure that occupational health professionals and the workforce are made aware of the risks posed by ototoxic substances; support their replacement or new technical measures to reduce exposure; make these substances a part of regular screening, develop tools that can early diagnose chemically induced hearing impairment, and investigate further into the ototoxic properties of these substances. Further research should focus on quantifying the combined effects of ototoxic substances and noise.
Keywords
carbon disulfide; carbon monoxide; hearing impairment; evidence-based risk assessment; lead; mercury; styrene; toluene; trichloroethylene; xylene
Hrčak ID:
83245
URI
Publication date:
15.6.2012.
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