Professional paper

Schonlein-Henoch Syndrome in children and adolescents: epidemiologic data and coagulation disturbances

Srđana Čulić ; Paediatric Clinic, Clinical Hospital Center Split, University of Split, Split
Željana Čukušić ; School of Medicine, University of Split
Marijan Saraga ; School of Medicine, University of Split, Split, Croatia
Branka Pauković-Sekulić ; Department of Clinical Laboratory Diagnostics, Križine, Split, CROATIA
Dubravka Kuljiš ; School of Medicine, University of Split, Split, CROATIA
Vitomir Metličić ; School of Medicine, University of Split, Split, Croatia
Jasminka Pavelić ; Division of Molecular Medicine, Ruđer Bošković Institute, Zagreb, Croatia

Abstract

The aim of the study was to examine the function of platelets in children and adolescents with Schönlein-Henoch Syndrome (SHS) presenting normal platelet count, and epidemiologic data. The most frequent SHS localization was the skin and joints. The most consistent defect in latelet aggregation was a block of the release of endogenous ADP when ADP was used as induction agent. In conclusion, our epidemiological data differ slightly from those observed by other authors. However, we have shown that increased tendency toward bleeding in SHS might be caused by function disturbances of platelets.

Keywords

SHS; epidemiology; platelet function, thrombocites

Hrčak ID:

83975

URI

https://hrcak.srce.hr/83975

Publication date:

4.6.2012.

Article data in other languages: croatian

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