Acta clinica Croatica, Vol. 50 No. 4, 2011.
Review article
Varicella Zoster Virus Reactivation in Hemodialysis Patients: Manifestations, Treatment, Complications and Outcome
Ines Mesar
Nikolina Bašić-Jukić
Tvrtko Hudolin
Lea Katalinić
Petar Kes
Abstract
Varicella zoster virus reactivation often occurs in the setting of impaired immunity, which is generally present in patients with end-stage renal disease (ES RD). Therapy for varicella zoster virus infection is well established. However, it is often been forgotten that acyclovir dosage should be adjusted to renal function. We point to the problem encountered in clinical practice when ES RD patient presents with cutaneous herpes zoster and neurological symptoms. Clinical findings alone may prove inadequate to determine whether neurological deficit is caused by infection of the central nervous system or is a consequence of acyclovir induced neurotoxicity.
Keywords
Encephalitis, varicella zoster; Antiviral agents; Kidney failure, chronic
Hrčak ID:
84492
URI
Publication date:
14.12.2011.
Visits: 2.565 *