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Successful Treatment of Brain Ischemia with Supplementation Therapy in a Patient with Hyperhomocysteinemia

Marjan Zaletel orcid.org/0000-0002-5121-5621
Aleš Ambrožič
Nataša Gašperšič
Matija Zupan
Bojana Žvan

Abstract

The effectiveness of homocysteine-lowering therapy on stroke prevention is still unclear. Although randomized controlled epidemiological trials have yielded mixed findings, a multicenter trial did not show any beneficial effect. Genetic studies are still lacking. Therefore, we report on a female patient with transient ischemic attacks and the thermolabile variant of methylenetetrahydrofolate reductase (TT genotype), who benefited from supplemental therapy for homocysteine lowering.

Keywords

Hyperhomocysteinemia; Ischemic attacks, transient; Methylenetetrahydrofolate reductase; Vitamins; Dietary supplement

Hrčak ID:

84587

URI

https://hrcak.srce.hr/84587

Publication date:

14.12.2011.

Article data in other languages: croatian

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