Original scientific paper
Dermatoglyphics in Patients with Hypothyreosis
Jelena Vučak Kulić
Jasna Miličić
Damir Letinić
Dario Rahelić
Dražen Zekanović
Abstract
About 15% of all females and 3% of all males suffers from hypothyreosis. The thyroid disease is the most frequent
cause of hypothyreosis, and among people in Croatia who are suffering from that disease 90% have been affected by its
autoimmune form. The thyroid diseases are supposed to be caused by the influence of various genetic and external factors
and some forms of genetic influences have not yet been studied. Analysis of digito-palmar dermatoglyphics has been used
in the research of the role of genetic predisposition in many various diseases. We have analyzed correlation of qualitative
and quantitative traits between the group of 50 females suffering from hypothyreosis and a control group of 100 phenotypically
healthy females. Quantitative statistical analysis using t-test has indicated only few significantly different
variables, while the discriminant analysis has shown 76.9% correctly classified samples. The factor analysis has shown
a high percentage of total variance within patients suffering from hypothyreosis, as well as the different structure of individual
factors. Qualitative analysis has shown the heterogeneity between the two examined groups. The results of the research
have proved that the qualitative characteristics are more unstable than the quantitative ones and they have also
shown the instability of genes taking part in hypothyreosis development implying genetic predisposition of the disease.
Keywords
hypothyreosis; dermatoglyphics; genetic predisposition
Hrčak ID:
84774
URI
Publication date:
10.7.2012.
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