Review article
An integrated framework of personalized medicine: from individual genomes to participatory health care
Andrea W.M. Evers
; Department of Medical Psychology, Radboud University, Nijmegen Medical Centre, Nijmegen, the Netherlands
Maroeska M. Rovers
; Department of Epidemiology, Biostatistics, and HTA, Radboud, University Nijmegen Medical Centre, Nijmegen, the Netherlands
Jan A.M. Kremer
; Department of Gynecology, Radboud University Nijmegen, Medical Centre, Nijmegen, the Netherlands
Joris A. Veltman
; Department of Human Genetics, Radboud University Nijmegen, Medical Centre, Nijmegen, the Netherlands
Jack A. Schalken
; Department of Urology, Radboud University Nijmegen Medical, Centre, Nijmegen, the Netherlands
Bas R. Bloem
; Department of Neurology, Radboud University Nijmegen, Medical Centre, Nijmegen, the Netherlands
Alain J. Van Gool
; Department of Laboratory Medicine, Radboud University, Nijmegen Medical Centre, Nijmegen, the Netherlands
Abstract
Abstract Promising research developments in both basic
and applied sciences, such as genomics and participatory
health care approaches, have generated widespread interest
in personalized medicine among almost all scientific
areas and clinicians. The term personalized medicine is,
however, frequently used without defining a clear theoretical
and methodological background. In addition, to date
most personalized medicine approaches still lack convincing
empirical evidence regarding their contribution and
advantages in comparison to traditional models. Here, we
propose that personalized medicine can only fulfill the
promise of optimizing our health care system by an interdisciplinary
and translational view that extends beyond
traditional diagnostic and classification systems.
Keywords
Hrčak ID:
85769
URI
Publication date:
15.8.2012.
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