Professional paper

Unicystic Ameloblastoma: Clinical Pathological Analysis of 22 Cases

Shelly Arora orcid.org/0000-0002-1277-6194 ; Senior Resident, Department of Oral Pathology, Maulana Azad Institute of Dental Sciences New Delhi, India
Priya Kumar ; Assistant Professor, Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India
Aadithya B. Urs ; Professor, Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India
Jeyaseelan Augustine ; Assistant Professor, Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi, India

Abstract

Objective: Unicystic ameloblastoma (UA) is a variant of solid or multicystic ameloblastoma. It is characterized as a distinct variant exhibiting less aggressive behavior and a lower rate of recurrence. The current study was carried out to correlate the clinical pathological findings of the studied series of UA with the other reviewed cases in the literature. Materials and Methods: A total of 22 cases of UA were obtained after reviewing 112 cases of ameloblastoma from the archives of Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, India over a five year period. All the cases were assessed for patient age, gender, location, radiographic features, clinical diagnosis, histopathological features, treatment and available follow-up data. Result: The series represents 22 cases of UA out of 112 cases of ameloblastoma seen during a 5 year period. The age at diagnosis ranged from 3-65 years and peaked during the 3rd decade of life with an almost equal gender predilection. The majority of the cases involved the mandible (n=19) and only 3 were seen in the maxilla. The size of the lesion ranged from 1.5x1cm to 7.4x2.8cm. A painless swelling was the most common presenting symptom and bony expansion was evident in 18 cases. Unilocular radiolucency was encountered in 20 and multilocular in 2 cases. Microscopically, all the 22 cases satisfied the criteria proposed by Philipsen and Reichart (Luminal-8, Luminal and intraluminal-4, Luminal, intraluminal and intramural- 3 and Luminal and intramural-7). Numerous variations in the lining epithelium were observed. The follow-up data were available for 16 patients and revealed no recurrence. Conclusion: The study has collected clinical, radiographic and histological data for 22 cases of UA. The histogenesis, diagnostic pitfalls as well as the need for prolonged follow-up of treated lesions have been emphasized.

Keywords

Ameloblastoma; Dentigerous Cyst; Mandible

Hrčak ID:

86883

URI

https://hrcak.srce.hr/86883

Publication date:

24.9.2012.

Article data in other languages: croatian

Visits: 3.086 *