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Acne and Diet: Facts and Controversies
Saida Rezaković
; Private Policlinic “Eskulap” Havidićeva 9/11 HR-10020 Zagreb Croatia
Zrinka Bukvić Mokos
; University Hospital Center Zagreb, Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Zagreb, Croatia
Aleksandra Basta-Jusbašić
; University Hospital Center Zagreb, Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Zagreb, Croatia
Abstract
Acne is a common skin disorder characterized by follicular hyperkeratinization
and obstruction of the pilosebaceous follicles, androgen stimulated
sebum production, colonization of the follicles by Propionibacterium acne,
and inflammation. A large number of epidemiological studies have shown a low
incidence of acne in non-Western societies, suggesting that diet might be an
important factor in acne pathogenesis, particularly in mediating inflammation,
oxidative stress and androgen stimulation in the acne process. Consequently, it
has been hypothesized that diet might have a preventive or therapeutic effect
in this skin disorder. Since the majority of recent data have not been consistent,
the aim of this article is to present current knowledge and scientific assumptions
on the relationship between diet and acne.
Keywords
acne vulgaris; diet; hyperinsulinism; insulin-like growth factor 1; fatty acids
Hrčak ID:
89111
URI
Publication date:
14.10.2012.
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