Review article
SECONDARY (AA) AMYLOIDOSIS IN CROHN’S DISEASE
TOMISLAV BULUM
; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
INGRID PRKAČIN
; University Department of Medicine, Merkur University Hospital, Zagreb,Croatia
GORDANA CAVRIĆ
; University Department of Medicine, Merkur University Hospital, Zagreb,Croatia
NIKOLA SOBOČAN
; University Department of Medicine, Merkur University Hospital, Zagreb,Croatia
BRUNO ŠKURLA
; University Department of Medicine, Merkur University Hospital, Zagreb,Croatia
LEA DUVNJAK
; Vuk Vrhovac Clinic for Diabetes, Endocrinology and Metabolic Diseases, Zagreb, Croatia
STELA BULIMBAŠIĆ
; Department of Pathology, Dubrava University Hospital, Zagreb, Croatia
Abstract
Amyloidosis is a clinical entity that results from deposition of an extracellular protein material that causes disruption in normal architecture and impairs function of multiple organs and tissues. Secondary amyloidosis (AA) is a rare but serious complication that occurs in the context of cancer, chronic inflammation and chronic infectious diseases, including inflammatory bowel disease, mainly long-standing Crohn’s disease. Renal failure is the most common clinical presentation of AA, ranging from nephrotic syndrome and impaired renal function to renal failure, with a potential for high morbidity. The incidence of the association of t. Bulum, i. Prka
Keywords
amyloidosis; Crohn’s disease; nephrotic syndrome
Hrčak ID:
89275
URI
Publication date:
17.10.2012.
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