Original scientific paper
Detection of Myocardial Ischemia in Diabetic Patients: The Limitations of Myocardial Perfusion Imaging
Tomislav Jakljević
; University of Rijeka, Rijeka University Hospital Center, Department of Cardiology, Rijeka, Croatia
Alen Ružić
; University of Rijeka, Rijeka University Hospital Center, Department of Cardiology, Rijeka, Croatia
Ksenija Baždarić
; University of Rijeka, School of Medicine, Department of Medical Informatics, Rijeka, Croatia
Luka Zaputović
; University of Rijeka, Rijeka University Hospital Center, Department of Cardiology, Rijeka, Croatia
Žarko Mavrić
; University of Rijeka, Rijeka University Hospital Center, Department of Cardiology, Rijeka, Croatia
Stephane Champagne
; »Henri Mondor« University Hospital, Department of Interventional Cardiology, Paris, France
Emmanuel Teiger
; »Henri Mondor« University Hospital, Department of Interventional Cardiology, Paris, France
Abstract
In the study of 286 patients with suspected coronary artery disease and recent exercise single photon emission computed tomography (SPECT) test, we performed coronary angiography with coronary fractional flow reserve (FFR) measurement and tested the differences between diabetic (103) and non-diabetic (183) patients in ischemia detection by this two methods. The diabetic patients had a higher prevalence of hypertension, higher BMI and cholesterol levels, as well as longer duration of hospitalization than non-diabetic patients. There was no difference found between groups according to the exercise SPECT test, but, there were significantly more negative results in the non-diabetic group than in the diabetic group according to the FFR test, also, the percentage of stenosis was higher in diabetic patients. The concordance between the two methods was found, it was fair in diabetic patients (k=0.25, 95% C.I. 0.06–0.45) and moderate in non-diabetic patients (k=0.49, 95 % C.I. 0.36–0.62).
Keywords
coronary artery disease; myocardial ischemia; computed emission single photon tomography; myocardial fractional flow reserve
Hrčak ID:
89427
URI
Publication date:
5.10.2012.
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