Review article

Radiological manifestations of musculo-skeletal complications in HIV-infected patients

Klaudija Višković ; Klinika za infektivne bolesti
Ivana Župetić ; KBC "Sr. milosrdnice", Zagreb, Hrvatska
Matej Mustapić ; KBC "Sr. milosrdnice", Zagreb, Hrvatska
Dina Miklić ; KBC "Sr. milosrdnice", Zagreb, Hrvatska
Zoran Brnić ; KB Merkur, Zagreb, Hrvatska
Josip Begovac ; Klinika za infektivne bolesti

Abstract

Patients with human immunodeficiency virus (HIV) infection are susceptible to a variety of complications that can affect musculosceletal system. Infection (cellulitis, necrotizing fasciitis, pyomyositis, osteomyelitis, septic arthritis) is the most common complication. Inflammatory conditions are either caused by the HIV infection itself or triggered by adaptive changes in the immune system. Muscular symptoms may result from rhabdomyolysis, myositis or from sideeffects of highly active anti-retroviral therapy (HAART). Non-Hodgkin lymphoma and Kaposi sarcoma are two most common neoplasms in this patient population. During the aging proces of HIV-infected patients osteopenia, osteoporosis and patologic fractures are observed, more frequently than in non-HIV infected patients. Radiology plays an important role in the early diagnosis and treatment planning. Especially important is the syndrom of osteonecrosis that is not very frequent and whose cause is not well known yet. It is important for the radiologist to be familiar with the different types of musculoskeletal diseases in HIV-infected patients so that an appropriate differential diagnosis can be established.

Keywords

HIV-infection; imaging findings; musculo-skeletal system; computorized tomography; magnetic resonance imaging

Hrčak ID:

92447

URI

https://hrcak.srce.hr/92447

Publication date:

26.3.2012.

Article data in other languages: croatian

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