Veterinary Archives, Vol. 71 No. 6, 2001.
Original scientific paper
Elimination of enterotoxigenic Escherichia coli in experimentally infected piglets by passive immunization with bovine colostral antibodies.
Nagendra Nath Barman
; Department of Microbiology, College of Veterinary Science, Guwahati, India
Dilip Kumar Sarma
; Department of Microbiology, College of Veterinary Science, Guwahati, India
Bhabendra Nath Neog
; Network Project, Indian Council of Agricultural Research, College of Veterinary Science, Guwahati, India
Abstract
When piglets fail to receive colostrum from the sow, as an alternative means passive immunization can be carried out with antibodies derived from non-maternal sources. In this study, pregnant cows were vaccinated intramuscularly and intramammarily with killed ETEC vaccine and developed a high level of colostral antibodies. These antibodies were specifically of IgG and IgA. Day-old piglets fed with colostrum containing a high titre of IgG survived the challenge infection. However, 75% piglets fed with colostrum from unvaccinated cows, and 100% piglets receiving no colostrum, died from challenge infection.
Keywords
E. coli; passive immunization; piglets
Hrčak ID:
92967
URI
Publication date:
19.12.2001.
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