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Acta medica Croatica : Časopis Akademije medicinskih znanosti Hrvatske, Vol. 66 No. 1, 2012.

Review article

NEUROLOGICAL DISORDERS IN PREGNANCY

GORDANA BROZOVIĆ ; University Department of Anaesthesiology, Resuscitation and Intensive Care Medicine, Sveti Duh University Hospital, Zagreb, Croatia
IVAN ŠKLEBAR ; University Department of Anaesthesiology, Resuscitation and Intensive Care Medicine, Sveti Duh University Hospital, Zagreb, Croatia
BRANKA MAZUL SUNKO ; University Department of Anaesthesiology, Resuscitation and Intensive Care Medicine, Sveti Duh University Hospital, Zagreb, Croatia
VLADIMIR BLAGAIĆ ; University Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Zagreb, Croatia

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Abstract

Preeclampsia is characterized by hypertension, peripheral edema and proteinuria, but very often also includes neurologic complications. Neurologic complications of severe preeclampsia are indentical to those of hypertensive encephalopathy. The most common neurologic symptoms are headache, vomiting, mental disorders, visual disturbances, sensorimotor deficits and seizures. Endothelial cell dysfunction is the main cause of multiorgan failure. It is of utmost importance to recognize these symptoms and initiate apropriate therapy. Systemic blood presure must not exceed the cerebrovascular autoregulatory capacity. Serum magnesium level is significantly decreased in pregnant women with severe preeclampsia and cerebral edema. Magnesium has been shown to be effective in reducing the occurrence of seizures in preeclampsia by decreasing neuronal excitability, protecting the endothelium against free radicals and reducing cerebral perfusion.

Keywords

neurologic disorders; pregnancy; preeclampsia

Hrčak ID:

93248

URI

https://hrcak.srce.hr/93248

Publication date:

30.10.2012.

Article data in other languages: croatian

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