Original scientific paper

Chromosome Aberrations and Micronucleus Frequency in Anaesthesiology Personnel

Ružica Rozgaj
Vilena Kašuba

Abstract

Occupational exposure to anaesthetic gases is associated with various adverse health effects. Genetic material is a sensitive target of numerous harmful agents. The aim of this study was to examine whether chromosomal damage could serve to indicate exposure to anaesthetics. Twenty-eight anaesthesiologists, 16 technicians, and 32 control subjects were examined for chromosome aberrations and micronucleus frequency. An increase in chromosome damage was found in both exposed groups. Micronucleus frequency increased significantly, showing higher rates in women. The observed differences between the sexes in respect to the exposure risk call for further, targeted investigation.

Keywords

anaesthetics; chromosome damage; genotoxicity; occupational exposure

Hrčak ID:

688

URI

https://hrcak.srce.hr/688

Publication date:

15.3.2001.

Article data in other languages: croatian

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