Original scientific paper
Controlled Drug Delivery and Ophthalmic Applications
J.A. Ferreira
; aCMUC-Department of Mathematics, University of Coimbra
P. de Oliviera
; University of Coimbra
P.M. da Silva
; Department of Physics and Mathematics, Coimbra Institute of Engineering
Abstract
The goal of this paper is to present an overview of drug delivery from polymeric therapeutic lens to the anterior segment of the eye. Mathematical models that describe in vitro and in vivo drug delivery, from different types of lens, are presented. Healthy and pathological situations are addressed. Numerical simulations are included and compared with experimental results.
Keywords
Controlled drug delivery; effective time; therapeutic lens; mathematical model; partial differential equations
Hrčak ID:
93990
URI
Publication date:
19.12.2012.
Visits: 1.157 *