Original scientific paper

Carotid Intima-Media Thickness in Patients with Chronic and Aggressive Periodontitis

Ivan Puhar ; Department of Periodontology, School of Dental Medicine, and Clinical Department of Periodontology, Clinical Hospital Center Zagreb, Zagreb, Croatia
Arijana Lovrenčić-Huzjan ; Clinical Department of Neurology, University Hospital Center “Sisters of Mercy”, Zagreb, Croatia
Darja Šodec-Šimičević ; Clinical Department of Neurology, University Hospital Center “Sisters of Mercy”, Zagreb, Croatia
Maja Strineka ; Clinical Department of Diagnostic and Interventional Radiology, Clinical Hospital Dubrava, Zagreb, Croatia
Darko Božić ; Department of Periodontology, School of Dental Medicine, and Clinical Department of Periodontology, Clinical Hospital Center Zagreb, Zagreb, Croatia
Darije Plančak ; Department of Periodontology, School of Dental Medicine, and Clinical Department of Periodontology, Clinical Hospital Center Zagreb, Zagreb, Croatia

Abstract

Objective: The objective of this study was to investigate the elationship between carotid intima-media thickness (IMT) and periodontal status in periodontitis patients. Materials and methods:
The study was conducted on 128 subjects divided into four groups. The test groups consisted of 37 patients with chronic periodontitis (18 men and 19 women, mean age 57.2±8.0 years) and 30 patients with aggressive periodontitis (13 men and 17 women, mean age 34.7±6.3 years). There were 27 subjects in the control group for chronic periodontitis (11 men and 16 women, mean age 53.0±10.1 years), and 34 subjects in the control group for aggressive periodontitis (15 men and 19 women, mean age 27.7±5.7 years). Both control groups consisted of periodontally healthy volunteers. Periodontal condition was assessed using periodontal indices. Triglycerides, HDL cholesterol, LDL cholesterol, total serum cholesterol, high sensitive C-reactive protein (hsCRP), and glucose levels were quantified in serum. IMT measurements on common carotid artery were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results: This research revealed significantly higher values of overall (0.8 mm) and right (0.8 mm) carotid IMT in chronic periodontitis patients only. Chronic periodontitis was a statistically significant predictor (p=0,003) for the right carotid IMT in the multivariate model, when potentially confounding factors were included. Both periodontitis groups mainly included nonsmokers, and had statistically higher levels of hsCRP (2.2 and 1.4 mg/L). Conclusions: The study demonstrated that chronic periodontitis can be linked with carotid atherosclerosis, but further research is required for a more precise assessment of the influence of aggressive periodontitis on carotid IMT.

Keywords

Periodontitis; Periodontal Index; Carotid Stenosis; Tunica Intima; C-Reactive Protein

Hrčak ID:

94352

URI

https://hrcak.srce.hr/94352

Publication date:

28.12.2012.

Article data in other languages: croatian

Visits: 2.267 *