Original scientific paper
Epigenetics, and Human Biology and Health Responses to Modernization in the Samoan Archipelago
Stephen T. McGarvey
; International Health Institute, Department of Epidemiology, Program in Public Health, Brown University, Rhode Island, USA
Abstract
Epigenetic mechanisms offer explanations for how environmental exposures at critical life periods may affect human biological and disease phenotypes. Incorporation of epigenetic approaches into research on health consequences of societal transitions may increase understanding of the complex biobehavioral factors influencing changing populations. Description of present and planned genetic epidemiology research, including epigenetic studies, among Samoans experiencing economic modernization and globalization offer examples for progress in knowledge of population health transitions.
Keywords
epigenetics; Samoans; cardiometabolic phenotypes; gene by environment interaction
Hrčak ID:
94857
URI
Publication date:
27.12.2012.
Visits: 815 *