Short communication, Note
Small Cell Neuroendocrine Tumor of the Larynx – A Small Case Series
Anton Mikić
; Clinical Center of Serbia, Institute of Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
Elvir Zvrko
; Clinical Center of Montenegro, Clinic of Otorhinolaryngology and Maxillofacial Surgery, Podgorica, Montenegro
Aleksandar Trivić
; Clinical Center of Serbia, Institute of Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
Dušan Stefanović
; Clinical Center of Serbia, Institute of Otorhinolaryngology and Maxillofacial Surgery, Belgrade, Serbia
Mileta Golubović
; University of Montenegro, School of Medicine, Podgorica, Montenegro
Abstract
Neuroendocrine tumors are the most common nonsquamous types of laryngeal neoplasms. They are classified as typical carcinoids, atypical carcinoids, small-cell neuroendocrine carcinomas, and paragangliomas. The aim of the paper is to present four patients with small-cell neuroendocrine tumor arising in larynx. There were one woman and three men whose ages were 47–77 years; all of them had metastases when first seen. The clinical presentation and management of such type of tumor are discussed. Small-cell neuroendocrine carcinomas are very aggressive neoplasms. Patients could benefit from surgery, but radiotherapy and chemotherapy remain the treatment of choice. Examination of a large series is
required to define the most useful diagnostic methods and the most successful treatment modalities.
Keywords
laryngeal cancer; small cell carcinoma; neuroendocrine tumors
Hrčak ID:
96507
URI
Publication date:
2.1.2013.
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