Professional paper
Oral Human Papilloma Virus (HPV) Infection in a HIV Infected Patient - a Case Report
Ana Cekić-Arambašin
; Stomatološki fakultet Sveučilišta u Zagrebu, Zavod za oralnu medicinu, Gundulićeva 5, 10000 Zagreb, Hrvatska
Peter Reichart
; Universitätsklinikum Charite, Medizinische Fakultät der Humboldt-Universität zu Berlin, Zentrum für Zahnmedizin, Abteilung für Oralchirurgie und zahnärztliche Röntgentechnologie, Föhrer Strasse 15, Berlin, Njemačka
Andrea Schmidt-Westhausen
; Universitätsklinikum Charite, Medizinische Fakultät der Humboldt-Universität zu Berlin, Zentrum für Zahnmedizin, Abteilung für Oralchirurgie und zahnärztliche Röntgentechnologie, Föhrer Strasse 15, Berlin, Njemačka
Abstract
A case of a patient with HIV disease and oral papillomatous lesions indicating HPV infection is reported. Diagnostic procedures included oral clinical diagnosis, histopathology and immunohistochemi- stry of the oral lesion (HPV identification), determination of the patient's immune status and evaluation of systemic diseases related to HIV infection. Results showed the patient to be anti-HIV positive and asymptomatic for HIV-associated diseases. As a homosexual, the patient belonged to the high risk group for HIV infection. The patient's CD4+- cell-count was not reduced (1000/pl). Oral diagnosis pointed to multiple papillomas of the mandibular vestibular mucosa, histopathology to papillary hyperplasia and chronic inflammation, whereas immuno- histochemistry confirmed HPV infection with HPV types 6, 11 and 18. It is concluded that the diagnostic procedure of HIV-related oral papillomatous lesions should always include demonstration ofHPV-types, some of which are particular for HPV-related lesions in HIV-infection.
Keywords
oral mucosa; human papilloma virus; HIV infection
Hrčak ID:
97565
URI
Publication date:
15.3.1999.
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