Original scientific paper
Usefulness of pulsed Doppler of lymph nodes in diagnosis of cervical lymphadenitis
Zoran Brnić
; KB "Merkur", Zavod za dijagnostičku i intervencijsku radiologiju, Zagreb, Hrvatska
Jelena Popić-Ramač
; KB "Merkur", Zavod za dijagnostičku i intervencijsku radiologiju, Zagreb, Hrvatska
Vedran Brnić
; Medicinski fakultet Sveučilišta u Zagrebu, Zagreb, Hrvatska
Abstract
We investigated the usefulness of Doppler in differentiation of the causes of cervical lymphadenopathy, and the decrease of vascular resistance as specific sign of lymphadenitis. Spectral Doppler analysis with measurements of resistance index (RI), pulsatility index (PI), peak systolic velocity (PSV) and enddiastolic velocity (EDV) was performed in 98 patients with metastatic, lymphomatous, inflammatory and normal cervical lymph nodes. The results were compared with findings of cytology and hystology or with clinical presentation and follow-up of patients. Significant differences for RI and PI were found between all groups of patients except between lymphomatous and normal lymph nodes. Specificity of 100% for metastases was found for cutoff values RI > 0.80 and PI > 1.80. Positive predictive value of 100% for acute lymphadenitis was shown for cutoff values RI < 0.50 and PI < 0.60. EDV > 9 cm/s has 100% negative predictive value and EDV < 1 cm/s has 100% specificity and positive predictive value for metastases. Although differences in RI, PI, PSV and EDV between different nodal diseases were found, only extreme cutoff values are helpful in differential diagnosis. The finding of very low vascular resistance is valuable in prediction of inflammatory etiology of lymphadenopathy.
Keywords
Vascular Doppler ultrasound; lymphadenopathy; differential diagnosis
Hrčak ID:
98233
URI
Publication date:
30.9.2012.
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