Review article
Use of Carbon Dioxide Laser for the Treatment of Early Squamous Cell Carcinoma and Severe Leukoplakia
Walter Niccoli-Filho
; Department of Biopathology and Diagnosis of Sao Paulo State University - UNESP, School of Dentistry, Sao Jose dos Campos - SP, Brazil
Indira Muliterno Rojo de Almeida
; Fellow, Sao Paulo State University, School of Dentistry, Department of Biopathology and Diagnosis, Sao Jose dos Campos, SP, Brazil
Denise Takehana dos Santos
; Dentistry Emergency Service, Sao Paulo State University - UNESP, School of Dentistry, Sao Jose dos Campos - SP, Brazil
Carlos Schwab
; Department of Physics at Advanced Studies Institute - IEAv, Lasers Division, Sao Jose dos Campos - SP, Brazil
Abstract
Leukoplakia is potentially a premalignant lesion and, in a small number o f cases, invasive carcinoma occurs at the same site. In recent literature, the commonly accepted rate of malignant transformation varies between 3 and 6%. Among the methods advocated for the treatment of these lesions are cryosurgery, chemical peel, surgical excision, and C 02 laser vaporization. In the following case, bilateral lesions in buccal mucosa with a 5-year history of development are presented. Utilizing local anesthesia, the involved surface epithelium and submucosa on each side were treated at 7-day interval with a continuous wave C 02 laser vaporization, 2.0 mm defocused spot at 10.0 watts. Mucosal destruction was carried out to the depth at which muscle fibers could be seen with arbitrary margins of approximately 5 mm. Lesions were followed up after 1, 3, 6, 9, and 12 months following surgery and there was neither recurrence nor any other intercurrent problems observed.
Keywords
leukoplakia; squamous cell carcinoma; carcinoma in situ; carbon dioxide laser; oral cancer
Hrčak ID:
98255
URI
Publication date:
15.12.1998.
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