Professional paper

Antihistamines - Aplication in Dental Medicine and Possible Undesirable Effects

Kata Rošin-Grget ; Department of Pharmacology, Faculty of Dentistry, University of Zagreb, Zagreb, Croatia
Ileana Linčir ; Department of Pharmacology, Faculty of Dentistry, University of Zagreb, Zagreb, Croatia

Abstract

In his practice the dentist comes across allergic reactions which can be detected in the oral cavity and orofacial region. In order to treat these reactions, as in the case of anaphylactic shock, the dentist applies antagonist H} receptor. Some antagonist H1 receptor can be
applied by the dentist because o f their sedative, antiemetic and of local anaesthetic effect. They are also used for reducing the secretion
o f saliva. During application o f antagonist H1 receptors with marked sedative effects the dentist must warn his patient of the possibility of reduced psychophysical ability. The dentist should keep in mind the fact that simultaneous application o f other depressors of the central nervous system leads to marked sedation. Antihistamines may interact with many other medications, which can also cause undesirable reactions. On the other hand, some undesirable effects which occur during longterm application of H} antagonists, can be seen in the oral cavity. Thus, such patients may ask for the dentist’s help because of xerostomia. Knowledge o f the characteristics o f this group o f medications enables the dentist to utilize their therapeutic value and prevent the possibility o f undesirable effects.

Keywords

H1 antagonists; application in dental medicine; undesirable effects

Hrčak ID:

98620

URI

https://hrcak.srce.hr/98620

Publication date:

15.3.1996.

Article data in other languages: croatian

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