Original scientific paper
Lymphocyte Values in Patients with Recurrent Aphthous Ulceration
Ana Cekić-Arambašin
; Department of Periodontology School of Dental Medicine University of Zagreb, Croatia
Suzana Brozović
; Department of Periodontology School of Dental Medicine University of Zagreb Croatia
Ksenija SRĐAK JOGRIĆ
; Oral Pathology Department
Abstract
The total number ofT(CD2+)- and B (CD20+)- lymphocytes as well as T lymphocyte subpopulations CD4 (helper) and CD8 (suppressor) were examined in peripheral blood of patients with RAU, to determine their role in the onset of this disease. The study was carried out in two groups: a group of patients with acute stage of RAU and a control group of healthy subjects. Lymphocyte values were determined in peripheral blood by the method of flow cytometry. The obtained results showed decreased B-lymphocyte values in peripheral blood in patients with RAU in relation to healthy subjects. However, T-lymphocytes showed increased values in 1/3 of the patients, which is statistically insignificant. CD4 lymphocyte values were also increased and statistically insignificant, while CD8 lymphocyte values were significantly decreased in patients with RA U in relation to healthy subjects.
Keywords
RAU; lymphocytes; peripheral blood
Hrčak ID:
99116
URI
Publication date:
15.6.1995.
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