Original scientific paper
The Use of Experimental Animals During Investigation of Dental Implants
Tihomir Švajhler
; Privatna stomatološka ordinacija, Zagreb, Hrvatska
Irina Filipović-Zore
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Pavel Kobler
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Darko Macan
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Abstract
The use of animals during investigations is an accepted method for
verification of current theoretical principles in medical practice. There
is almost no species or subspecies of the animal world on which scientific research has not been carried out. The laboratory rats, dogs, chimpanzees and pigs are most often used in stomatological investigations. Each new dental implantation system requires strict scientific and clinical verification before its commercialisation. Experiments on animals are an unavoidable part o f basic investigations, e.g. testing the toxicity of dental implants, investigation of its biocompatibility, and evaluation o f the success of the form (design). Scientific approach to investigations o f dental implants began in the 1950’s, and scientific methods o f research are daily becoming sophisticated, and criteria for clinical evaluation more rigid.
The paper describes a basic investigation o f a new implantation system, DPI, carried out on beagle dogs as the experimental model. The investigation was performed entirely in the Department for Oral Surgery School of Dental Medicine University o f Zagreb. Results o f the investigation confirm that the DPI system is a good, usable, outstanding design, biocompatible and oseointegrative. The beagle dog proved to be a good experimental model for testing dental implants.
Keywords
dental implant; experimental model; beagle dog
Hrčak ID:
99397
URI
Publication date:
15.9.1997.
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