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Serum Prolactin Levels in Behçet’s Disease. Is There a Relationship between Behcet’s Disease and Prolactin as in Other Autoimmune Diseases?

Atil Avci ; Training and Research hospital of Kayseri
Deniz Avcı ; Training and researc hospital of Kayseri


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Abstract

OBJECTIVE: Serum prolactin levels rise in so many diseases concerning autoimmune. To demonstrate the relationship between the Behçet Disease that has a  common  trend of being defined as an autoimmune multisystem disease and the level of serum prolactin, an immunstimulant hormon of adenohypophysis and to check the literature and including our results among them, we have looked the prolactin levels of patients  who are active in dermatological diagnosis and do not take any cure for the disease and we have searched whether there is relationship between the disease and serum prolactin levels

MATERIAL AND METHODS: 43 patients were taken for the study.21 female and 22 male.20 healthy people similar in age and sex were used in the control group. Patients in Behçet group were in the active period of their illnesses in terms of oral apthe , genital apthe , erythema nodosum  and patergy(+). In addition, artralgia accompanied the chart in 20 patients.

RESULTS: Male prolactin average in Behçet group was 11.63 and in control group it was 10.19. There was not a significant prolactin level difference between the two groups (t=1.272, p=0.264.). Female prolactin average in Behçet group was 9.84 and it was 7.21 in Control group.The difference was not meaningful in terms of statistical evaluation.

CONCLUSION: No meaningful difference was detected both in Behçet and Control group in terms of prolactin. In our study, as a result unlike it was observed in some other auto-immune disease events, a relation between Behçet disease and prolactin could not been introduced.

Keywords

Hrčak ID:

101621

URI

https://hrcak.srce.hr/101621

Publication date:

10.5.2013.

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