Original scientific paper

Characteristics of inheritance of hypodontia in families

Anamarija Ožanić-Marof ; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Ilija Škrinjarić ; School of Dental Medicine, University of Zagreb, Zagreb, Croatia

Abstract

The aim of this study was to assess the prevalence of hypodontia and microdontia in a population, along with the main characteristics of their genetic transsmission. A group iof 513 school children from the district of Celje were examined. On the basis of clinical examination and X-ray analysis, hypodontia was found in 2.9% and microdontia in 3.3% of the population. In patients with established anomalies, a genealogical analysis of family generations was performed in order to determine the type of trait inheritance within a family. Hypodontia was found to be transmitted as an autosomal dominant trait with a complete or incomplete penetrance and variable expressivity. In some cases, it may be transmitted according to a polygenic model. The finding of one of these types of transmission in some cases would not rule out the possibility of different modes of transmission in other situations. Concurrent findings of hypodontia and microdontia appear to confirm previous hypotheses on identical genetic background of these two anomalies.

Keywords

hypodontia; microdontia; genetic transmission

Hrčak ID:

101758

URI

https://hrcak.srce.hr/101758

Publication date:

15.3.1987.

Article data in other languages: croatian

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