Original scientific paper

Quantification of Intraocular IFNg and IgG in Cataract and Diabetes

Joško Pavan ; University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, Zagreb, Croatia
Jasminka Salopek-Rabatić ; University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, Zagreb, Croatia
Snježana Kaštelan ; University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, Zagreb, Croatia
Anđela Jukić ; University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, Zagreb, Croatia
Krešimir Vicković ; University of Zagreb, Dubrava University Hospital, Department of Ophthalmology, Zagreb, Croatia

Abstract

The anterior eye chamber is called the immunologically privileged place. The inflammatory disturbances in the interior of the eye chamber are characterised primarly by the changes of the IFN-gamma, IgG and IL-4 concentration and appearance of the oligoclonal IgG. In type I diabetes, there are antibodies to the beta cells of the pancreas, IgG class (among others such as antiretinal antibodies) and they are also found in preretinal membranes of diabetics. In type II there are IgG antibodies to insulin receptors.

Keywords

diabetes; retinopathy; cataract; machine learning; C5.0; aqueous humor; serum; IgG; prognosis; barrier

Hrčak ID:

102821

URI

https://hrcak.srce.hr/102821

Publication date:

22.4.2013.

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