Review article
Helicobacter Pylori Detection in Histological Samples
Jasminka Jakić-Razumović
; KBC Zagreb
Nadan Rustemović
; KBC Zagreb
Abstract
Histological examination of endoscopic gastric mucosa in patients with dyspeptic signs has a great value in the recognition of preneoplastic mucosal changes and conditions related to chronic gastric mucosa inflammation, which carries some risk for stomach carcinoma. In this way, a gastroenterologist can get the relevant prognostic factors and criteria for patients follow-up. The prerequisite for the appropriate histological examination is the amount of the obtained biopsy samples. At least five biopsy samples from different sites in the stomach, as generally accepted, yield optimal results in histological analysis. Furthermore, the parameters for reporting all preneoplastic conditions, which are described by the new OLGA staging system and which may lead to the development of carcinoma, such as gastric mucosa atrophy, should be standardized. The Modified Sydney Score (Houston System) is still used by some institutions for reporting atrophy score and H. pylori colonization.
Keywords
gastritis; histological criteria; H. pylori
Hrčak ID:
102972
URI
Publication date:
18.4.2013.
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