Review article

The Role of Azithromycin in the Treatment of Infections Caused by Shiga Toxin–Producing Enteroaggregative Escherichia coli 0104:H4

Dalibor Vukelić ; Klinika za infektivne bolesti “Dr. Fran Mihaljević”

Abstract

An outbreak of Shiga toxin–producing enteroaggregative Escherichia coli (STEC O104:H4) infection with a high incidence of haemolytic uremic syndrome (HUS) occurred in Germany in May 2011. Antibiotic therapy is widely used to treat enteroaggregative E. coli infection but antibiotic treatment of STEC infection is discouraged because it might increase the risk of HUS development. In the German outbreak, a noticeable number of patients received azithromycin treatment. Treatment with azithromycin was associated with a lower frequency of long-term STEC 0104 H4 carriage, and it did not affect the incidence of HUS.

Keywords

Escherichia coli; Shiga toxin; haemolytic uremic syndrome; azithromycin

Hrčak ID:

102976

URI

https://hrcak.srce.hr/102976

Publication date:

18.4.2013.

Article data in other languages: croatian

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