Original scientific paper

Structure-Radical Scavenging Activity Relationships of Flavonoids

Dragan Amić ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P.O. Box 719, HR-31107 Osijek, Croatia
Dušanka Davidović-Amić ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P.O. Box 719, HR-31107 Osijek, Croatia
Drago Bešlo ; Faculty of Agriculture, The Josip Juraj Strossmayer University, P.O. Box 719, HR-31107 Osijek, Croatia
Nenad Trinajstić ; The Rugjer Bošković Institute, P.O. Box 180, HR-10002 Zagreb, Croatia

Abstract

The relationship between the structural characteristics of 29 flavonoids and their antiradical activity was studied. The obtained results suggest that the free radical scavenger potential of these polyphenolic compounds closely depends on the particular substitution pattern of free hydroxyl groups on the flavonoid skeleton. The possible mechanism of action of flavonoids lacking B ring OHs as free radical scavengers has been proposed.

Keywords

flavonoids; free radical scavenging activity; structure-activity relationships

Hrčak ID:

103057

URI

https://hrcak.srce.hr/103057

Publication date:

30.4.2003.

Visits: 8.976 *