Original scientific paper

The estimation of anemia degree in patients after heart valve replacement and coronary artery bypass surgery

Gordana Laškarin ; Zavod za fiziologiju i imunologiju, Medicinski fakultet, Sveučilište u Rijeci, Rijeka
Viktor Peršić ; Klinika za prevenciju, liječenje i rehabilitaciju bolesti srca i krvnih žila „Thalassotherapia – Opatija”, Opatija
Goran Pinjuh ; Studij medicinsko-laboratorijske dijagnostike, Medicinski fakultet, Sveučilište u Rijeci, Rijeka
Josip Laginja ; Klinika za prevenciju, liječenje i rehabilitaciju bolesti srca i krvnih žila „Thalassotherapia – Opatija”, Opatija
Marko Boban ; Klinika za prevenciju, liječenje i rehabilitaciju bolesti srca i krvnih žila „Thalassotherapia – Opatija”, Opatija
Božena Ćurko-Cofek ; Zavod za fiziologiju i imunologiju, Medicinski fakultet, Sveučilište u Rijeci, Rijeka
Janja Kuharić ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet, Sveučilište u Rijeci, Rijeka
Milan Ličina ; Klinika za internu medicinu, KBC Rijeka, Rijeka
Vlatka Sotošek Tokmadžić ; Katedra za anesteziologiju, reanimatologiju i intenzivno liječenje, Medicinski fakultet, Sveučilište u Rijeci, Rijeka

Abstract

Aim: To determine the presence, type and degree of anemia in patients after heart
valve replacement and coronary artery bypass grafting during the first three weeks of early
stationary medical rehabilitation. Patients and methods: Data were obtained by analyzing
medical records of the subjects following the approval of the Ethics Committee of Special hospital
for medical rehabilitation of heart, lungs and rheumatism „Thalassotherapy – Opatija”
from Opatija in accordance with all applicable guidelines in basics of good clinical practice and
the Declaration of Helsinki. Research included 145 patients with coronary artery bypass and
67 patients with heart valve replacement. Both groups were divided into a group of men and
women, and the results were compared with healthy subjects using nonparametric Kruskal-
Wallis and Mann-Whitney U test. Results: In the group of women and men after heart valve
replacement surgery and coronary artery bypass grafting the number of erythrocytes, hemoglobin
concentration and hematocrit were significantly decreased compared to the control
group (all P < 0,001), but no significant difference in hematological indexes were found. Discussion: In patients under observation there are changes
in erythrogram in reducing the number of normochrome and
normocyte erythrocytes, although the changes are not profound
to declare the anemia. Because of the known increased
mortality rates of anemia in cardiac patients, we should look
for anemia, evaluate and determine its cause, in order to provide
appropriate treatment in time. Conclusions: It is a condition
that can be treated relatively easily with iron and very
cautiously with drugs stimulating erythropoesis, particularly
in patients with kidney insufficiency. It can prevent or decrease
need for blood transfusions, which carry more side effects
in cardiac patients.

Keywords

anemia; biological valves; coronary artery bypass; coronary heart disease; heart valve diseases; mechanical valves

Hrčak ID:

103485

URI

https://hrcak.srce.hr/103485

Publication date:

5.6.2013.

Article data in other languages: croatian

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