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Collegium antropologicum, Vol. 37 No. 2, 2013.

Original scientific paper

Mucositis Grades and Yeast Species

Marina Ognjenović ; University of Split, School of Medicine, Split, Croatia
Katja Milatić ; University of Zagreb, School of Dental Medicine, Zagreb, Croatia
Katica Parat ; University of Split, School of Medicine, Split, Croatia
Ivan Kovačić ; University of Split, School of Medicine, Split, Croatia
Marina A. Ježina Bušelić ; »Marina A. Ježina« Private Dental Clinic, Split, Croatia
Joško Božić ; University of Split, School of Medicine, Split, Croatia

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Abstract

Surgically treated patients with oral, head and neck cancer commonly develop mucositis during additional irradiation therapy. Oral mucosa inflammation other than irradiation is mostly caused by Candida albicans, yeast of Candida genus. This study evaluated possible connection between grades of oral mucositis and oral yeast profile in irradiated patients before, during and after irradiation. In 25 examined patients mucosits grades »0« to »2« before irradiation with
20% positive smears and only two different species of yeasts (C. krusei 4%, C. albicans 16%) during the irradiation changed into »0« to »4« and 36% positive smears with five different species of oral yeasts (C. albicans 12%, C. glabrata 12%, C. parapsilosis 4%, C. guilliermondii 4% and Saccharomyces cerevisiae 4%). Three weeks after irradiation was finished mucositis decreased into »1« to »3« with 20% positive smears and again only two species of yeasts (C. albicans 16%, C. guilliermondii 4%). Mucositis grades was increased significantly (p=0.0037) with changes in fungi profile.

Keywords

oral mucositis; oral yeasts; irradiation

Hrčak ID:

104480

URI

https://hrcak.srce.hr/104480

Publication date:

1.7.2013.

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