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Renal Adenocarcinoma Presenting As a Spontaneous Perirenal Hematoma in a Patient on Warfarin Therapy – Case Report and Literature Review

Miroslav Tomić ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, Clinical Department of Urology, Zagreb, Croatia
Monika Ulamec ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, »Ljudevit Jurak« Department of Pathology, Zagreb,
Davor Trnski ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, Clinical Department of Urology, Zagreb, Croatia
Jordan Dimanovski ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, Clinical Department of Urology, Zagreb, Croatia
Marija Spajić ; Karlovac General Hospital, Department of Pediatric Nephrology, Karlovac, Croatia
Davor Tomas ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, »Ljudevit Jurak« Department of Pathology, Zagreb,
Božo Krušlin ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, »Ljudevit Jurak« Department of Pathology, Zagreb,
Borislav Spajić ; University of Zagreb, »Sestre milosrdnice« University Hospital Center, Clinical Department of Urology, Zagreb, Croatia


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Abstract

We are presenting a rare case of a spontaneous extensive perirenal hematoma caused by ruptured renal adenocarcinoma in a patient who was on warfarin therapy because she had atrial fibrillation and three myocardial infarctions. A 77-year-old woman was admitted to our department with acute right flank pain and hemorrhagic shock. The anamnestic data revealed no trauma and hematuria. Abdominal ultrasonography and computed tomography scan showed large
retroperitoneal hematoma. The patient underwent urgent surgery and radical nephrectomy was performed. A large retroperitoneal
hematoma was found originating from a ruptured renal neoplasm in the upper pole of the right kidney. The pathohistological diagnosis was chromophobe renal cell carcinoma. The clinical, diagnostic and therapeutic peculiarities of this rare condition are presented, along with the literature review on the topic.

Keywords

chromophobe renal cell carcinoma; renal neoplasm; warfarin therapy; retroperitoneal hematoma; spontaneous rupture

Hrčak ID:

104761

URI

https://hrcak.srce.hr/104761

Publication date:

1.7.2013.

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