Original scientific paper
The effect of Zovirax cream in recurrent herpes labialis
Iva Vidas
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Kata Rošin-Grget
; School of Dental Medicine, University of Zagreb, Zagreb, Croatia
Abstract
The efficiency of the Zovirax cream in the treatment of recurrent herpes labialis was studied in 30 patients with either prodromal symptoms, advanced clinical picture of the disease with erythema and vesicles with serous content or complicated by secondary infection. In another group of 30 patients with identical clinical pictures, recurrent herpes labialis was treated with Viru-Merz ointment, zincoxide paste and Garamycin ointyment. Zovirax cream was shown to be therapeutically most efficient during the prodromal phase of the disease as well as in the advanced clinical picture, i. e. within 3— 4 days from the onset of the disease. In the prodromal phase of the disease, the therapeutic effect of Zovirax was not statistically significantly different from that achieved by Virumerz ointment, whereas in the vesicular stage of recurrent herpes labialis the success of former therapy was found to be statistically significantly higher as compared to therapy with other agents applied. In complications of recurrent herpes labialis due to pyogenic bacteria, however, broad-spectrum antibiotic antments were observed to elicit a better therapeutic effect.
Keywords
Hrčak ID:
105118
URI
Publication date:
15.6.1987.
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