Original scientific paper

Sensitivity of endodontis microbiological population to antibiotics

Dora Najžar-Fleger ; Zavod za bolesti zubi Stomatološkog fakulteta, Zagreb
Vera Čoklica ; Zavod za bolesti zubi Stomatološkog fakulteta, Zagreb
Zdenko Njemirovskij ; Zavod za bolesti zubi Stomatološkog fakulteta, Zagreb
Vesna Čapo ; Zavod za bolesti zubi Stomatološkog fakulteta, Zagreb

Abstract

The purpose of the work was to determine the sensitivity of microorganisms isolated during the endodontic treatments performed between 1976 and 1981 to antibiotics (amphicillin, carbenicillin, cloxacillin, cephalexin, canamycin, neomycin, garamycin, geomycin, erythromycin, lincomyoin, cloramphenicol, colimycin, nistatin and canesten) on the basis of 4,436 antibiograms. The sensitivity to antibiotics was analyzed by using the disk method at the Institute for Health Protection of the Socialist Republic of Croatia. As amphicillin, cephalexin and erythromycin (the last one in higher daily doses) turned out to be the most efficient of all the analyzed antibiotics, they should be selected for endodontic treatments. Cloxacillin and lincomycin are not recommended as they act on staphylococci less efficiently than amphicillin. Among the Gram negative bacteria, enterococci showed the highest resistance to antibiotic therapy. They reacted best to amphicillin and very little to lincomycin. Aminoglucoside, garamycin, neomycin and amphicillin produced a good effect on the Gram negative bacteria. Escherichia coli showed the highest sensitivity to neomycin. Fungi showed a much lower sensitivity to nistatin than to canesten. It is recommended to apply -antibiotics critically as they cannot substitute inadequate endodontic treatments and they cannot make up for the absence of aseptic work in endodontics.

Keywords

endodontic microbiology; antibiotic susceptibility

Hrčak ID:

105753

URI

https://hrcak.srce.hr/105753

Publication date:

15.9.1981.

Article data in other languages: croatian

Visits: 1.995 *