Review article

Antibiotic therapy in endodontics

Dora Najžar-Fleger ; Zavod za bolesti zuba Stomatološkog fakulteta, Zagreb
Zdenko Njemirovskij ; Zavod za bolesti zuba Stomatološkog fakulteta, Zagreb

Abstract

Microbiological findings of bacterial endocarditis from the University Hospital for Infectious Diseases Dr. Fran MihaIjević in Zagreb are presented and compared to the findings collected at the University of Michigan Hospital during the approximately same period (1962 — 1975). A change in infection ecology has been observed in technically more advanced environment. In the choice of antibiotics in endodontics the priority is given to penicillin antbiotics and alternatively to cephalosporins and erythromycin. For the protection of persons predisposed to bacterial endocarditis only bactericidal
antibiotics are used. The best ones are penicillins and cephalosporins, which are administered perorally two hours before the endodontic treatment or parenterally half an hour before the treatment in sufficiently high doses. In some cases a combination of antibiotics is necessary as well as the consultation with the physician following up the patients condition after curing the basic disease. The combination of penicillin antibiotics and aminoglucosides applied with due caution, which is necessary because of ototoxic and nephrotoxic aminoglucoside action, is considered to be the best one. The local application of antibiotics combined with hidrocortisones is contraindicated in persons predisposed to bacterial endocarditis.

Keywords

endodontics; antibiotics; bacterial endocarditis

Hrčak ID:

105770

URI

https://hrcak.srce.hr/105770

Publication date:

15.12.1981.

Article data in other languages: croatian

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