Original scientific paper

SOME QEEG PARAMETERS AND GENDER DIFFERENCES IN SCHIZOPHRENIA PATIENTS

Nensi Manuševa orcid.org/0000-0002-7601-2505 ; University Clinic of Psychiatry, Skopje, Republic of Macedonia
Antoni Novotni ; University Clinic of Psychiatry, Skopje, Republic of Macedonia
Stojan Bajraktarov ; University Clinic of Psychiatry, Skopje, Republic of Macedonia
Beti Zafirova-Ivanovska ; Institute of Epidemiology and Biostatistics, Faculty of Medicine, Skopje, Republic of Macedonia

Abstract

Background: Gender issues are extensively explored in schizophrenia. A mounting body of research evidence suggests that there
are gender differences in the age at onset, duration of untreated psychosis and presented psychopathology. In recent years, in order
to obtain neurophysiologic explanation for the disturbed behavior and thinking in schizophrenia, numerous studies have been
performed focusing on the QEEG parameters. However, the results were inconclusive. The aim of this study was to investigate the
gender differences in some clinical and QEEG parameters in schizophrenia patients.
Subjects and methods: Thirty schizophrenia patients were enrolled in the study (M/F ratio 13/17; mean age 34 years). The
QEEG parameters which were analyzed were amplitude, mean frequency and relative power of the main bands of the basic activity.
Clinical assessment was performed using the PANSS, BPRS and CGI scales.
Results: QEEG parameters demonstrating statistically significant difference were amplitude and relative power in beta activity
and lower mean theta frequency over left frontal, temporal and parietal regions in female patients who also had statistically
significant differences in PANSS and BPRS scores.
Conclusion: Differences in amplitude and relative power in the beta bands in female schizophrenic patients are associated with
more severe actual psychopathology. Considering the relatively small sample, the current results must be replicated with a larger
group of drug-free patients to confirm the findings.

Keywords

schizophrenia; gender; QEEG; PANSS

Hrčak ID:

106203

URI

https://hrcak.srce.hr/106203

Publication date:

25.3.2012.

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